Critical new data on the effects of marijuana on memory

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Critical new data on the effects of marijuana on memory

I have known it for decades that marijuana has a negative effect on memory and can cause serious problems with both short-term and long-term recall.

What was not known, however, was how the drug works. Recent research has revealed possible mechanisms by which marijuana can affect memory.

Here’s how memory works...

While the brain comprises neurons, it also contains astroglia cells that perform many of the brain’s supporting functions. Although astroglia are not neurons, neurons cannot function without astroglia.

Astroglia provide food for neurons, structurally support their position in the brain matrix, regulate the fluid in which the brain bathes, and have been shown to conduct neurotransmitters such as glutamate.

About 50% of your brain cells are astroglia, not neurons. That’s why the evidence that THC (the active ingredient in marijuana) affects astroglia is very concerning.

What is the specific effect of THC on astroglia and how does it affect memory?

Astroglia are part of the system that connects neurons in long synaptic chains. If these connections are disrupted, so are the synaptic chains themselves, which are the basis of memory.

By disrupting these chains, chronic or long-term marijuana use can create memory problems, or memory lapses. Because THC also depletes neurotransmitters like glutamate, it can prevent astroglia, and even neurons, from functioning properly, leading to further short-term memory problems.

So we see here that THC’s action on the brain can affect both short- and long-term memory.

It is important to note that we usually relate these memory problems to chronic or heavy marijuana use, as occurs when a person suffers from a substance addiction. This addiction can be physical, recreational, or psychological. With marijuana, it is most often psychological.

The occasional user may suffer from short-term memory loss. An example would be someone who uses marijuana perhaps once a fortnight. However, it is unlikely that such an occasional user would experience long-term memory problems.

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Interesting experiments that have explored the link between marijuana and memory

We have conducted interesting experiments based on this new knowledge about how marijuana causes memory loss. We conducted one crucial study on rats, in which we injected THC into the rats.

The rats that were under the influence of THC had extreme problems not only with memory but also with rational thinking. As a result, the rats on THC were twice as bad at navigating and processing mazes as the rats who were not on THC.

Given that a maze is a problem, both in terms of rational thinking and memory, this experiment shows how disruptive the effects of THC are to the mammalian brain. However, this is a study done on rats. Many studies done on humans point to this serious problem.

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